Hull KR are 13/4 to claim another Super League scalp when they head to Salford Red Devils in the sixth round of the Challenge Cup on Friday.
The Robins are sitting top of the Kingstone Press Championship, after 12 wins from 13 games, as they aim to secure an immediate return to Super League.
Tim Sheens’ side claimed a 23-10 win at Leigh in the previous round with half-back Jamie Ellis instrumental against his former club.
Salford, who had Justin Carney sent off, survived a scare against Canadian newcomers Toronto Wolfpack to prevail 29-22 at the AJ Bell Stadium.
Having survived last season’s Million Pound Game – beating Hull KR 19-18 with a golden-point extra-time win - the Red Devils are enjoying a fine season.
They are third in Super League with nine wins from 13 matches and are 11/50 to avoid elimination from the cup and 10/1 to win it.
Also that night, Rovers’ city rivals – and holders - Hull FC welcome Catalan Dragons to the KCOM Stadium and are priced at 6/25 to advance.
The French side were beaten by the Airlie Birds at the same venue in the quarter-finals last season and are 3/1 to gain some revenge.
There are two other all-Super League ties with Castleford hosting St Helens on Saturday and Widnes heading to Warrington on Sunday.
Castleford, the Super League leaders, were beaten finalists in 2014 and are 11/50 for the victory with Saints – who last lifted the cup in 2008 – at 13/4.
Warrington, beaten by Hull in last year’s showpiece, are 1/6 to get past Widnes (4/1), with the Vikings’ last cup success coming 33 years ago.
Wigan Warriors are the 13/4 favourites to win the cup with Warrington 9/2, Castleford and Leeds 5/1 and Hull FC 7/1.