Phil Taylor is 10/1 to sign off his Premier League career with a seventh title at the O2 Arena on Thursday night.
The 16-time world champion will make his final appearance in the 16-week competition in London after announcing his retirement from the sport following this year's World Championship.
Taylor is looking to add to his jam-packed silverware cabinet with a trophy that he has not claimed since beating Simon Whitlock in 2012.
But 'The Power' faces strong competition to reach a second consecutive final, where he lost to Michael van Gerwen last year, as he takes on in-form Peter Wright in the semis.
Taylor is priced at 13/8 to claim only his second victory in eight Premier League meetings with Wright, who is the 1/2 favourite to triumph in his first last-four appearance.
Taylor has an exceptional record in Premier League semi-finals, winning eight of 11, and has triumphed in four of his last five fixtures.
Yet Wright, 4/1 to win the tournament, has taken his game to another level this year and is currently on a four-match winning streak, meaning a close game is expected.
The semi-final could go to the wire, with odds of 8/5 and 37/10 for over 17.5 and 18.5 legs respectively, while Taylor is 12/1 to win 10-9.
Van Gerwen is the favourite to claim a second consecutive title at 13/25.
The Dutchman takes on Gary Anderson in the semis, in a repeat of last week's clash in Scotland and the 2015 Premier League final.
Van Gerwen laid down a marker in Aberdeen by claiming an impressive 7-4 success, despite heading into the match in Anderson's homeland on the back of a defeat to Taylor in Sheffield and a whitewash by Wright in the final of the European Darts Grand Prix.
The world number one has won all four of his semi-finals in the Premier League and, at 3/10, is expected to advance to the final.
Anderson has won both Premier League finals he has participated in, in 2011 and 2015 respectively, but only has a 50 per cent win ratio in four semis, one of which came against Van Gerwen in 2014.
Van Gerwen is 7/1 to win 10-6 while Anderson, 11/2 to win the tournament, can be backed at 51/20 to pull off an upset.